{"title":"Longevity \u0026 Cellular Healthspan","description":"\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan\u003eCutting-edge longevity \u0026amp; healthspan supplements — NMN, Fisetin, Berberine, CoQ10. NAD+ support and senolytic research.\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"lion-s-mane-extract","title":"Lion’s Mane Extract","description":"\u003cp\u003e\u003cstrong\u003eWhat it is \u0026amp; why it matters\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLion’s Mane (\u003cem\u003eHericium erinaceus\u003c\/em\u003e) is a medicinal mushroom traditionally used in East Asia for cognitive and nerve support. It contains unique compounds (hericenones and erinacines) that have been shown in early research to stimulate Nerve Growth Factor (NGF), a protein involved in the growth and maintenance of neurons. This makes it one of the most interesting natural compounds currently being studied for brain health.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEvidence rating:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e⭐⭐⭐\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003ePromising (Emerging)\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e— Early human research and strong mechanistic data are encouraging, but larger, well-controlled clinical trials are still needed before strong claims can be made.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSimple Dosage (updated 2026 guidance)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTypical studied dose:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003e1,000–3,000 mg per day of Lion’s Mane extract (often standardised for hericenones or erinacines).\u003c\/li\u003e\n\u003cli\u003eMost human studies used 1,000–2,000 mg daily, split into 1–2 doses.\u003c\/li\u003e\n\u003cli\u003eConsistency over many weeks appears more important than high single doses. Effects, when seen, have sometimes declined after supplementation stopped.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTake with or without food. No loading phase is required.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/biohacknz.com\/blogs\/research\/lion-s-mane-promising-but-still-emerging-research\" title=\"Lion's Mane: Promising research\"\u003e→\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eLearn more in our full research summary\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003ch3\u003eWhy Lion’s Mane is being studied for different people\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eLion’s Mane for Brain Health \u0026amp; Cognition\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEarly research, including a small human trial, suggests Lion’s Mane may support cognitive function in older adults with mild cognitive impairment. Mechanistic studies show it can stimulate NGF, which plays a role in neuron growth and survival. While promising, current evidence is still limited and larger studies are needed.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/biohacknz.com\/pages\/lion-s-mane-for-brain-health-cognition\" title=\"Lion's Mane for Brain Health and Cognition\"\u003e→\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eLearn more in our full research summary: “Lion’s Mane for Brain Health \u0026amp; Cognition”\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLion’s Mane for Healthy Ageing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAs we age, maintaining cognitive resilience becomes increasingly important. Lion’s Mane is being researched for its potential to support nerve health and neuroplasticity over time. Current data is still early-stage, but the NGF-stimulating properties make it an interesting compound for long-term brain health strategies.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/biohacknz.com\/pages\/lions-mane-for-healthy-ageing\" title=\"Lion's Mane for Healthy Ageing\"\u003e→\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eLearn more in our full research summary: “Lion’s Mane for Healthy Ageing”\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLion’s Mane for Mood \u0026amp; Mental Health\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eOne small human study found improvements in mood, anxiety, and sleep quality in overweight adults taking Lion’s Mane. However, this study had limitations (small sample size and no placebo control), so results should be interpreted with caution. It offers an interesting signal but is not yet conclusive.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/biohacknz.com\/pages\/lions-mane-for-mood-and-mental-health\" title=\"Lion's Mane for Mood and Mental Health\"\u003e→\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eLearn more in our full research summary: “Lion’s Mane for Mood \u0026amp; Mental Health”\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eExpert view:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eMycologist Paul Stamets and neuroscientist Dr. Andrew Huberman have both discussed Lion’s Mane, noting its unique NGF-stimulating compounds. They view it as promising but stress that larger human trials are still needed before strong claims can be made.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eThis is not medical advice. BioHackNZ provides general information based on published research. This is a complementary supplement and is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any supplement regimen. Individual results vary.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cstrong\u003eLast updated:\u003c\/strong\u003e 22 August 2026 | BioHackNZ Research Team\u003c\/p\u003e","brand":"BioHackNZ","offers":[{"title":"Default Title","offer_id":47638924329196,"sku":null,"price":0.0,"currency_code":"NZD","in_stock":false}]},{"product_id":"berberine","title":"Berberine","description":"\u003cp\u003e\u003cstrong\u003eBerberine\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eWhat it is \u0026amp; why it matters\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBerberine is a natural plant compound (an alkaloid) found in several traditional herbs. It activates AMPK — often called the body’s “metabolic master switch” — the same pathway that exercise and certain medications influence. Human research shows berberine can support healthy blood glucose regulation, cholesterol balance, and metabolic function. It is popular in the longevity and metabolic health communities as a complementary tool, but it is not a replacement for prescribed medication.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eEvidence rating:\u003c\/strong\u003e ⭐⭐⭐⭐ \u003cstrong\u003eStrong\u003c\/strong\u003e for blood glucose and metabolic markers in clinical studies; use remains complementary and should be discussed with a doctor if you take medications.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eSimple Dosage (from research)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e500 mg, 2–3 times daily with meals\u003c\/strong\u003e (total 1,000–1,500 mg per day) is the most common range used in human trials.\u003c\/li\u003e\n\u003cli\u003eTaking it with food improves absorption and reduces the chance of digestive upset.\u003c\/li\u003e\n\u003cli\u003eSome people start lower and build up. Dihydroberberine is a related form that may offer better bioavailability at lower doses.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eConsistency with meals matters. Do not use as a substitute for prescribed diabetes or cholesterol medication.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eWhy Berberine is useful for different people\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eBerberine for Metabolic Health\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eMultiple meta-analyses of randomised trials show berberine can support healthier fasting glucose, HbA1c, and insulin sensitivity markers. It is one of the better-researched natural compounds in this area, though results vary between individuals and it should only be used under appropriate medical guidance if you have a diagnosed metabolic condition.\u003c\/p\u003e\n\u003cp\u003e→ Learn more in our full research summary: “Berberine for Metabolic Health”\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eBerberine for Foundational Health\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBecause berberine activates AMPK (a pathway linked to cellular energy sensing and metabolic efficiency), many people use it as part of a broader metabolic and cellular health strategy alongside diet, movement, and sleep.\u003c\/p\u003e\n\u003cp\u003e→ Learn more in our full research summary: “Berberine for Foundational Health”\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eBerberine for Healthy Ageing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSupporting healthy metabolic function becomes increasingly relevant with age. Berberine’s effects on AMPK and metabolic markers make it a compound of interest for those focused on long-term metabolic resilience.\u003c\/p\u003e\n\u003cp\u003e→ Learn more in our full research summary: “Berberine for Healthy Ageing”\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eImportant notes\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBerberine can interact with a number of medications (including some diabetes drugs, statins, and blood thinners). Digestive side effects (cramping or loose stools) are relatively common, especially when starting. Always check with your healthcare provider before using berberine if you take any prescription medicines or have a medical condition.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eThis is not medical advice. BioHackNZ provides general information based on published research. This is a complementary supplement and is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any supplement regimen. Individual results vary.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLast updated:\u003c\/strong\u003e 23 August 2026 | BioHackNZ Research Team\u003c\/p\u003e","brand":"BioHackNZ","offers":[{"title":"Default Title","offer_id":47892690338028,"sku":null,"price":0.0,"currency_code":"NZD","in_stock":false}]},{"product_id":"coenzyme-q10-coq10-ubiquinol","title":"CoQ10 (Ubiquinol)","description":"\u003cp\u003e\u003cstrong\u003eWhat it is \u0026amp; why it matters\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCoQ10 is a natural compound your body makes and uses in every cell to produce energy (ATP) and protect against oxidative stress. Levels of CoQ10 decline with age and can also be reduced by certain medications, including some statins. Taking a high-quality CoQ10 supplement (especially the ubiquinol form) supports cellular energy, heart muscle function, and antioxidant defences. The strongest evidence is for its use as complementary support alongside standard care for heart function, and as a potential aid for muscle comfort in some people taking statins.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEvidence rating:\u003c\/strong\u003e ⭐⭐⭐⭐ \u003cstrong\u003eStrong\u003c\/strong\u003e as complementary support for heart function; ⭐⭐⭐ \u003cstrong\u003ePromising\u003c\/strong\u003e for statin-associated muscle comfort and healthy ageing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSimple Dosage (updated 2026 guidance)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e100–200 mg per day\u003c\/strong\u003e is a solid everyday dose for general cellular energy and healthy ageing support.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e200–300 mg per day\u003c\/strong\u003e (often split) is the range used in many of the stronger heart-related trials.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTake with a meal that contains some fat for better absorption. Ubiquinol is generally the better-absorbed form, especially for people over 40. Consistency matters more than perfect timing. No loading phase needed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy CoQ10 is useful for different people\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCoQ10 for Heart Health\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe heart has very high energy demands. Landmark trials (including Q-SYMBIO) and recent meta-analyses show that CoQ10, when used as an adjunct to standard therapy, may support better symptoms, reduced hospitalisations, and improved functional measures in people with heart failure. It is not a replacement for prescribed treatment.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/pages\/coq10-for-heart-health\"\u003e→ Learn more in our full research summary: “CoQ10 for Heart Health”\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCoQ10 for Statin Support\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eStatins can lower CoQ10 levels. Some people experience muscle discomfort as a result. Research (including a 2025 meta-analysis) suggests CoQ10 may help reduce the intensity of muscle symptoms in some statin users, which can support comfort and adherence to prescribed therapy.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/pages\/coq10-for-statin-support\"\u003e→ Learn more in our full research summary: “CoQ10 for Statin Support \u0026amp; Muscle Comfort”\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCoQ10 for Healthy Ageing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eCoQ10 production declines with age. Supporting cellular energy and antioxidant capacity becomes increasingly relevant for maintaining vitality, heart function, and overall resilience as we get older.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/pages\/coq10-for-healthy-ageing\"\u003e→ Learn more in our full research summary: “CoQ10 for Healthy Ageing”\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eThis is not medical advice. BioHackNZ provides general information based on published research. This is a complementary supplement and is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any supplement regimen, especially if you have a heart condition or take statins or other prescription medications. Individual results vary.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLast updated:\u003c\/strong\u003e 23 August 2026 | BioHackNZ Research Team\u003c\/p\u003e","brand":"BioHackNZ","offers":[{"title":"Default Title","offer_id":48208129982700,"sku":null,"price":0.0,"currency_code":"NZD","in_stock":false}]},{"product_id":"nicotinamide-mononucleotide-nmn","title":"NMN (Nicotinamide Mononucleotide)","description":"\u003cp\u003e\u003cstrong\u003eWhat it is \u0026amp; why it matters\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNMN is a direct precursor to NAD+, a molecule every cell in your body needs to produce energy, repair DNA, and keep cellular systems running smoothly. NAD+ levels naturally decline as we age. Taking NMN helps replenish this important molecule. Human trials show it reliably raises blood NAD+ levels and is generally well tolerated. The strongest research signals so far include improved muscle insulin sensitivity in postmenopausal women with prediabetes, and supportive effects on walking speed and sleep quality in older adults.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEvidence rating:\u003c\/strong\u003e ⭐⭐⭐⭐ \u003cstrong\u003eStrong\u003c\/strong\u003e for raising NAD+ levels; ⭐⭐⭐ \u003cstrong\u003ePromising\u003c\/strong\u003e for selected metabolic and functional outcomes in specific populations.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSimple Dosage (based on current human trials)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e250–600 mg per day\u003c\/strong\u003e is the most common effective range used in positive human trials for raising NAD+ and supporting functional outcomes.\u003c\/li\u003e\n\u003cli\u003eSome studies used up to 900 mg with additional signals for walking performance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eTake consistently, preferably in the morning. No loading phase is required. Timing is less important than daily consistency.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy NMN is useful for different people\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNMN for Healthy Ageing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNAD+ declines with age. NMN helps support cellular energy production and has shown signals for maintaining walking speed and improving sleep quality in older adults — both important for staying independent and feeling good as the years go by.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/pages\/nmn-for-healthy-ageing\"\u003e→ Learn more in our full research summary: “NMN for Healthy Ageing”\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNMN for Foundational Health\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBecause NAD+ sits at the centre of cellular energy production, many people use NMN as a foundational daily support for overall cellular function, especially once they move past their 40s.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/pages\/nmn-for-foundational-health\"\u003e→ Learn more in our full research summary: “NMN for Foundational Health”\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNMN for Women’s Health\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe strongest metabolic outcome trial for NMN was conducted in postmenopausal women with prediabetes. It showed improved muscle insulin sensitivity — a meaningful finding for women navigating midlife metabolic changes.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/pages\/nmn-for-womens-health\"\u003e→ Learn more in our full research summary: “NMN for Women’s Health”\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNMN for Performance \u0026amp; Energy\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNMN supports the cellular energy systems that power both body and brain. Some trials have reported better walking distance at higher doses, although evidence for classic sports performance (strength, power, muscle mass) remains limited and should be viewed with caveats.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/pages\/nmn-for-performance-energy\"\u003e→ Learn more in our full research summary: “NMN for Performance \u0026amp; Energy”\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eThis is not medical advice. BioHackNZ provides general information based on published research. This is a complementary supplement and is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any supplement regimen. Individual results vary.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLast updated:\u003c\/strong\u003e 23 August 2026 | BioHackNZ Research Team\u003c\/p\u003e","brand":"BioHackNZ","offers":[{"title":"Default Title","offer_id":48222702534892,"sku":null,"price":0.0,"currency_code":"NZD","in_stock":false}]}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0823\/8497\/8156\/collections\/collection-longevity-hero.jpg?v=1776846115","url":"https:\/\/biohacknz.com\/collections\/longevity.oembed","provider":"BioHackNZ","version":"1.0","type":"link"}